Urine microalbumin 150mg/L can be caused by a variety of reasons, there are physiological factors such as a lot of exercise, fatigue, etc. and pathologic factors such as diabetic nephropathy, hypertensive nephropathy, primary renal damage and so on. According to different causes, different treatments are adopted. Commonly used methods such as lifestyle modification, medication, renal replacement therapy and so on. 1. Physiological factors: If it is caused by physiological factors, such as a lot of exercise, standing for a long time, staying up late, fatigue and other factors. Then patients are advised to pay attention to rest and drink more water. 2. Diabetic nephropathy: If it is caused by diabetic nephropathy with urinary microalbumin 150mg/L, you can choose to use hypoglycemic and renal preservation drugs for treatment, such as acarbose tablets, irbesartan and other drugs. 3. Hypertensive nephropathy: If the urine microalbumin 150mg/L caused by hypertensive nephropathy, it is recommended to choose antihypertensive drugs, diuretics and other drugs, such as valsartan, furosemide tablets and so on to treat. 4. Primary renal damage: mainly glomerular damage, when the glomerular basement membrane is damaged resulting in increased permeability, it can lead to the excretion of albumin, causing elevated urine microalbumin. Commonly used drugs are hormones such as methylprednisolone and immunosuppressants such as cyclophosphamide, etc. When the development of uremia, renal replacement therapy such as hemodialysis can be performed. Patients with urine microalbumin 150mg / L, it is recommended to go to the hospital as soon as possible, under the guidance of the physician active treatment.