Irregular spots on a man’s face may be the manifestation of melasma, age spots and other diseases, which may be related to genetic factors, skin aging, drug factors, disease factors and other factors. 1. Chloasma: chloasma is a patch with different sizes and clear edges, which can be yellowish brown or brown in color, etc. Its etiology is more complicated, and it may be related to genetic factors, long-term ultraviolet irradiation, changes in the level of sex hormones, disease factors (thyroid disease, liver and kidney insufficiency, etc.), drug factors (long-term use of chlorpromazine, etc.), and so on. 2. Age spots: a kind of skin degeneration in the elderly, manifested as one or several yellowish or light brown flat papules or plaques. The occurrence of age spots may be related to natural aging of the skin, sunlight damage and other factors. Men with irregular spots on the face may also be caused by other diseases, generally speaking, the cause of the plaque is more, and complex, but also may be the result of a variety of factors, it is recommended that patients go to the regular hospital, clear cause, follow the doctor’s instructions for symptomatic treatment.