Because calcium oxalate stones are very hard and difficult to dissolve in urine, there is no better way to dissolve calcium oxalate stones, and larger stones are usually treated with surgery. Calcium oxalate stones are very dense and therefore very hard, and are difficult to dissolve in the urine and pass out of the body, and there is no good drug that can really dissolve calcium oxalate stones. If the calcium oxalate stones are large and cause fluid retention in the ureters or kidneys, they need to be evaluated by a physician and then treated with surgery. Depending on the diameter of the stone, different surgical methods are used. For stones with a diameter of 5-20mm, the stone can be crushed by extracorporeal ultrasound, followed by increased water intake to facilitate the expulsion of the stone from the body; if the stone is larger than 20mm in diameter or in a higher position, the stone can be crushed by percutaneous nephrolithotripsy or ureteroscopy to remove the stone. In addition to the above treatments, increased water intake should be used to prevent stone formation.