Normal creatinine indicates that the kidney function is still normal, but high urine protein indicates that there is already kidney-related disease, which is very common in clinical practice, because the early stage of many kidney diseases only shows abnormal urine tests, which can show an increase in urine protein, but there is no damage to kidney function, such as in the early stage of glomerulonephritis and nephrotic syndrome are positive for urine protein, while the kidney function is completely normal. It is only when the kidney disease progresses to a certain degree that the creatinine will increase. It is necessary to evaluate the specific condition and clarify the cause of the disease, and further clarify the diagnosis by checking the 24-hour urine protein quantification, kidney puncture biopsy and other related items for targeted treatment.