Elevated platelets up to 450 x 10^9/L will mainly increase the risk of embolism.
1. The normal reference range of platelets is (100-300)×10^9/L. Elevated platelets lead to viscous blood, slow hemodynamics, and hypercoagulable state of blood, so they are prone to thrombotic events, such as myocardial infarction, cerebral infarction, pulmonary embolism, and venous embolism of the lower extremities.
2. Oral aspirin can be taken to prevent thrombosis, but it is necessary to improve the examination to clarify the cause, platelet elevation has secondary factors, such as iron deficiency anemia, infection, tumor, etc. will make the platelet mildly to moderately elevated; primary factors mainly include primary thrombocythemia, myelofibrosis. The risk of thrombosis decreases when platelets are normalized by symptomatic treatment.
Specific disease diagnosis and treatment should be carried out under the guidance of physicians.