Coughing after micro-infiltrating lung adenocarcinoma surgery may be a normal reaction after surgery, or it may be caused by postoperative lung infection, tumor recurrence, etc., which can be treated by rest, oral dextromethorphan, levofloxacin and other medicines, surgery, radiotherapy and so on. 1. Normal reaction after surgery: after micro-invasive lung adenocarcinoma surgery, there will be some soft tissue damage and edema in the surgery area, which will cause irritating cough, after rest and rehabilitation, the tissue damage and edema will get better gradually, and the patient’s cough symptom will disappear; if the cough is serious, the patient can take dextromethorphan, diphenhydramine and other cough suppressants as prescribed by doctor for symptomatic treatment. 2. Post-operative lung infection: after micro-invasive lung adenocarcinoma surgery, patients with low resistance will easily suffer from bacterial and viral infections, which will cause pneumonia, and the inflammation stimulation will lead to the increase of bronchial and alveolar secretion, which will cause coughing, so patients can take levofloxacin, amoxicillin, acyclovir, and other anti-infective and anti-viral medicines as prescribed by doctors. 3. Tumor recurrence: tumor recurrence may also occur after micro-invasive lung adenocarcinoma surgery. Tumor recurrence compresses bronchial tubes and causes bronchial stenosis, resulting in irritating cough, which can be treated by surgical resection, radiotherapy, chemotherapy and so on. Coughing after micro-invasive lung adenocarcinoma surgery should go to the hospital in time to improve the examination and give targeted treatment after clarifying the cause of the disease.