Ureteral cancer may be related to occupation, but also heredity, Balkan nephropathy, drugs and other factors. 1. Occupation: At present, it is believed that workers engaged in chemical, petroleum, plastic products and other industries, as well as those who are in contact with coal or coke, asphalt are the high-risk groups of ureteral cancer. Aniline dyes, β-naphthylamine and benzidine are important carcinogens, and the latency period of ureteral cancer caused by these carcinogens is usually more than 15 years. 2. Heredity: Hereditary ureteral cancer usually develops at a younger age and is more common in females. Li-Fraumeni syndrome is a very rare chromosomal dominant syndrome, which can present with bilateral upper urothelial carcinoma. 3. Balkan nephropathy: Balkan nephropathy is a degenerative interstitial disease of the kidney, which often has a family history. In some areas, patients with Balkan nephropathy are 100~200 times more likely to develop uroepithelial cancer. Cancer of renal pelvis and ureter caused by Balkan nephropathy is mostly bilateral, and the cancer is well differentiated, low-graded and slow-growing. 4. Analgesic drugs: current research has confirmed that the abuse of analgesic drugs (especially finasteride) is one of the risk factors of renal pelvis and ureter cancer. Besides, there are many other reasons that can cause ureteral cancer, if you have ureteral cancer, you should seek medical treatment in time.