Which is more painful, gastroscopy or bronchoscopy, cannot be generalized and is mainly affected by the individual’s sensitivity and tolerance level. Gastroscopy is through the oral cavity, pharynx, esophagus, stomach to duodenal descending, mainly for the human body of the esophagus, stomach, duodenal mucosal lesions and a means of examination. During the operation, patients mainly have a foreign body sensation and nausea, and generally do not produce significant pain. Bronchoscopy is inserted through the nasal cavity or the oral cavity to examine the internal condition of the bronchial tubes, which is mainly a kind of examination means for the trachea, bronchial tubes and lungs of the patients. During the procedure, the patient feels irritation in the throat and the sensation of coughing. Gastroscopy and bronchoscopy are both interventional tests, and local anesthesia will be applied to the throat before the operation. However, it is inevitable that the process will cause irritation to the digestive tract and respiratory tract, resulting in discomfort. However, as pain is a subjective feeling, subject to the individual’s physical tolerance level and sensitivity to pain, and can not be directly compared to the pain. If an individual is more sensitive to pain and has a lower pain tolerance level, he/she can choose painless bronchoscopy and painless gastroscopy to reduce pain if he/she has good cardiopulmonary function.