It is generally not recommended to use ibuprofen and naproxen alternately, because ibuprofen and naproxen both belong to non-steroidal anti-inflammatory and analgesic drugs. If used interchangeably, it may aggravate the damage of the drug to the liver or kidney on the one hand, and on the other hand, it may aggravate some irritation of the drug to the gastrointestinal tract, so when choosing ibuprofen or naproxen, it is recommended to choose one of them. It should be noted that the use of ibuprofen or naproxen is only recommended when the body temperature is 38.5°C or above when using these drugs to reduce fever. When using these drugs to reduce fever, the body may sweat, which may cause the body to lose weight, so be sure to drink plenty of warm water when using fever-reducing drugs.