High creatine kinase isoenzyme mostly indicates damage to the heart muscle. It is best to have a heart ultrasound to check for damage to the heart muscle when creatine kinase isoenzyme is high. If the condition is not serious, you can get relief through dietary therapy, such as eating more fresh vegetables and fruits to replenish the body with vitamins. Try not to do too much gravitational activity, live a life of cold prevention, get enough sleep, be in a good mood, and control blood pressure, which can also be treated by taking cardiac nutritional drugs. If the high creatine kinase isoenzyme is related to infection, the infection needs to be controlled, and the creatine kinase isoenzyme will usually return to normal levels after the infection is eliminated. Elevated creatine kinase isoenzyme may also be associated with myocardial infarction, hypothyroidism, cerebrovascular disease, lung disease, etc. It is best to seek early medical attention.