Lysosomes are small bodies containing a series of acidic hydrolytic enzymes enclosed by a single lipoprotein membrane in the cell plasma. Lysosomes contain many types of hydrolytic enzymes and are capable of breaking down many kinds of substances, and they are likened to an intracellular enzyme warehouse digestive system. The enzymes in lysosomes are all hydrolytic enzymes, and the pH is generally 5, so they are all acidic hydrolytic enzymes. The enzymes in the lysosomes, if released, will digest the entire cell. They are generally not released into the internal environment and are mainly digested intracellularly. Congenital lysosomal disorders are a group of metabolic genetic disorders caused by the congenital deficiency of a certain lysosomal enzyme due to mutations in certain genes on the chromosome. Patients have a defective enzyme or enzyme structure, which prevents the corresponding substrate from being degraded in the cell and stored in the secondary lysosomes, resulting in impaired cellular metabolism. Congenital lysosomal disease is a type of metabolic genetic disorder caused by the congenital lack of a lysosomal enzyme due to mutations in certain genes on the chromosome. It is also called lysosomal storage disease because the corresponding substrates in the cell cannot be degraded and are stored in secondary lysosomes due to enzyme deficiency or enzyme structural defects, resulting in impaired cellular metabolism. Mucopolysaccharide storage disease is a group of diseases that occur when acidic mucopolysaccharide molecules (aminoglucan) cannot be degraded due to lysosomal enzyme defects, resulting in large deposits of mucopolysaccharides in tissues and increased excretion of mucopolysaccharides in urine.