Prevention of lysosomal enzyme defects

  Lysosomes are small bodies containing a series of acidic hydrolytic enzymes enclosed by a single lipoprotein membrane in the cell plasma. Lysosomes contain many types of hydrolytic enzymes and are capable of breaking down many kinds of substances, and they are likened to an intracellular enzyme warehouse digestive system. The enzymes in lysosomes are all hydrolytic enzymes, and the pH is generally 5, so they are all acidic hydrolytic enzymes.  The enzymes in the lysosomes, if released, will digest the entire cell. They are generally not released into the internal environment and are mainly digested intracellularly. Congenital lysosomal disorders are a group of metabolic genetic disorders caused by the congenital deficiency of certain lysosomal enzymes due to mutations in certain genes on chromosomes.  Prevention of lysosomal enzyme defects In addition to epidemiological surveys, carrier detection, population genetic and environmental monitoring, marriage and fertility guidance to reduce the incidence of genetic diseases in the population and improve the quality of the population, effective preventive measures must be taken for individuals to avoid the birth of offspring with genetic diseases (i.e., eugenics) and the occurrence of genetic mutations. The usual measures taken include: premarital examination, genetic counseling, prenatal examination and early treatment of genetic diseases.