It is possible that having two brands of rabies vaccine may have an effect on the amount of rabies neutralizing antibodies produced in the end, as well as on the duration of the antibodies, but the effect is generally not considered to be particularly large. Because rabies vaccine, as long as the complete injection of four or five shots, or even only three injections, rabies neutralizing antibodies can be produced, only if the process is not followed, or the number of injections is not complete, rabies neutralizing antibodies may not last too long. So rabies vaccination with two brands is done as a last resort, but it is also important to follow the post-exposure five-shot method as much as possible. If the injection is not done in this way, there is indeed a possibility that rabies-neutralizing antibodies will be affected to some extent. However, as long as the five injections are given intact, rabies neutralizing antibodies can still be effectively maintained for three to five years, or at least a year, so they can still have a rabies prevention effect.