Acne, or facial acne, recurrent acne is often accompanied by enlarged pores. The main target is to give anti-infection, inhibit sebaceous gland secretion and other drug treatment, at the same time pay attention to strengthen skin care. 1. Acne is a chronic inflammatory skin disease, the main clinical manifestations, including pimples, pustules, cysts and nodules, etc., due to the disease and sebaceous gland secretion abnormality related to, so generally will be accompanied by large pores, in the treatment of the main target is to give some anti-inflammatory (mupirocin) and inhibit sebaceous gland secretion of drugs (retinoic acid cream) treatment. 2. Enlarged pores, generally appearing in the bilateral cheeks and nose, the current clinical can be improved by carbon dioxide laser and other photoelectric treatment; hydrophobic injection by adding an appropriate amount of botulinum toxin can also inhibit sebaceous gland secretion pathway to improve the enlarged pores. Different diseases in the treatment program will have certain differences, but in the treatment process must pay attention to good skin care, keep the skin clean and dry and avoid extrusion, etc., in the choice of medication, be sure to go to the regular hospitals and strictly comply with medical advice.