1. Antibiotics should be used only in the following cases: a. when there is obvious symptoms of bacterial infection such as yellow-green pus or cough and yellow pus sputum; b. when symptoms are aggravated with fever, sore throat and increased nasal discharge; c. when symptoms are significantly relieved after short-term use of antibiotics in the past and aggravated after discontinuing antibiotics; d. when symptoms of nasal congestion, pus or snoring are obvious d. Those who have no significant improvement after nasal spray treatment with adrenocorticotropic hormone alone and wish to try the drug treatment again before surgery. 2. Principles of antibiotic use: a. Do not use it easily. Only use in the case of 1 above; b. To use should be sufficient. Strictly in accordance with the doctor’s orders, do not reduce the dosage and the number of times to use; c. To use to use enough course of treatment. The doctor thinks it can be stopped. d. Choose a sensitive antibiotic. Generally speaking, the most sensitive antibiotics for sinusitis bacteria are amoxicillin clavulanate potassium and third-generation cephalosporin antibiotics, such as cefixime. c. Choose the method of medication carefully. Generally speaking oral administration is the most common method. Intravenous drips should only be applied when oral administration is ineffective. Generally speaking, intranasal drops of antibiotics are not advocated and are prone to allergy and resistance. 3. How long should antibiotics be used? Generally speaking, they should be used until one week after the condition of 1 has improved. If there is no significant improvement after 4 weeks of continuous use, it should be re-examined to determine whether there is any deviation in diagnosis, whether the medication method (including the use of drugs other than antibiotics) is correct, and whether other kinds of antibiotics should be chosen. Finally, consideration should also be given to whether conservative treatment has failed and surgery is required.