Hormone-dependent dermatitis refers to the treatment of inflammatory dermatoses due to the continuous or intermittent topical application of glucocorticoids or cosmetics containing glucocorticoids for a longer period of time, and the symptoms are significantly improved. Due to the sudden discontinuation of the drug, the primary lesions worsen or new lesions appear at the site of drug use, accompanied by pruritus and burning pain. If glucocorticosteroids are used again, the signs and symptoms may improve quickly, and if the drug is stopped again the rash recurs and gradually worsens. Forcing patients to use glucocorticosteroids for a long time, resulting in hormone-dependent dermatitis. The main reason for this disease is that many people are influenced by advertisements and blindly use steroidal drugs such as dermatoplanin and fluorescence, and some people even use them directly as cosmetics. In addition, some patients are also caused by the use of hormone-like ‘healing cosmetics’ in beauty salons. Some patients also use hormone-like cosmetics in beauty salons, or use preparations containing hormone drugs that are not approved by the State Drug Administration. Hormone-dependent dermatitis is characterized by thinning of the skin, capillary dilation, flushing of the skin, skin flaking and aging, increased and longer fine hair, acne-like dermatitis, hyperpigmentation, cosmetic intolerance, and irritability. For the treatment of hormone-dependent dermatitis, less severe cases can be directly discontinued to reduce hormonal drugs; most of the treatment should be taken to gradually reduce the dosage of hormonal drugs, by slowly reducing the intensity and concentration of hormone use and avoiding the rebound that occurs when the drugs are suddenly stopped. Or topical tacrolimus ointment (a new type of topical anti-inflammatory drug), which mainly acts on inflammation-related cells and at the same time can promote skin collagen synthesis and skin barrier restoration, so theoretically this drug can not only replace the anti-inflammatory effect of hormone preparations, avoid the adverse reactions such as skin atrophy and capillary dilation caused by long-term topical hormone use, but also improve to a certain extent the It can also improve the skin barrier damage caused by long-term topical hormone application.