Bile duct cancer bilirubin more than 350mg/dL, the specific survival rate needs to be analyzed in combination with the treatment effect, personal situation, but staging. For patients with early stage of bile duct cancer, they can choose radical surgical resection in time, the success rate reaches 15%~25%, and the survival rate is about 30% in 5 years, and if they are more sensitive to the treatment and the efficacy is relatively more prominent, the survival rate will be enhanced. However, as soon as some patients are detected with bile duct cancer, it is in advanced stage, at this time, they have lost the best period for surgery, and it is easy to recur after surgery, and the survival rate within 5 years is less than 5%. At present, bile duct cancer patients with high bilirubin detected should control bilirubin in time to prevent aggravation of the disease. During this period, liver function should also be rechecked regularly, and if liver function is found to be impaired, liver-protecting tablets should be taken orally as prescribed by doctor. Meanwhile, it is also necessary to regularly observe the metastasis or spread of cancer cells, if found to have metastasized through lymph nodes or peripheral tissues and organs, radiotherapy should be given in time to inhibit the cancer cells, so as to avoid shortening the survival rate.