Whether infiltrating lung adenocarcinoma can be performed sublobar resection needs to be considered according to the patient’s physical condition, clinical stage and other factors. Early stage infiltrating lung adenocarcinoma can be performed sublobar resection, while intermediate stage and advanced stage patients need to undergo other treatments. Most of the invasive lung adenocarcinoma originates from bronchial mucosa epithelium, and early stage patients are asymptomatic, and with the development of the disease, it manifests as coughing, bloody sputum and chest pain. Sublobar resection can be considered for early stage of invasive lung adenocarcinoma, but it is applicable to lesions less than 2cm. If invasive lung adenocarcinoma develops into middle or advanced stage, sublobar resection is generally not suitable, and middle-stage patients are preferred to have lobectomy plus hilar mediastinal lymph node dissection; advanced patients need to have neoadjuvant chemotherapy, and some of the advanced patients can have stereotactic radiotherapy or targeted therapy. Patients diagnosed with invasive lung adenocarcinoma should receive timely treatment and choose the suitable treatment plan under the guidance of doctors to avoid delaying their condition.