There are many reasons why it is hard to say what you feel at night when you sleep on your calves, and the common ones are calcium deficiency, muscle strain, and restless leg syndrome. 1. Calcium deficiency: due to insufficient calcium intake, absorption disorders or calcium regulation disorders, there can be twitching of the hands and feet, difficult to sleep at night calves. 2. Muscle strain: due to excessive activities, the muscles are in a state of tension for a long time which exceeds the compensatory capacity of the muscle tissues, limiting the local blood circulation and causing symptoms such as pain, weakness and acidity, which can be gradually manifested. 3. Restless legs syndrome: indescribable discomfort in both lower limbs at rest, often aggravated at night when resting, with a strong desire to move the legs, when returning to rest after the activity, the discomfort symptoms tend to reappear. The cause is unclear and may be genetically related. The indescribable feeling in the calves at night may have other causes such as phlebitis, etc. It is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, and then targeted treatment under the guidance of the doctor.