The medical community has yet to reach a definitive conclusion on the cause and pathogenesis of osteoarthritis, but osteoarthritis usually occurs as a result of a combination of age, obesity, inflammation, trauma, and genetic factors. The etiology of primary osteoarthritis is not fully understood, and it has been clinically found that older and overweight individuals are more likely to develop osteoarthritis. It is generally believed that it may be related to cartilage nutrition, metabolic disorders, and stress imbalances leading to it. Secondary osteoarthritis refers to secondary changes that occur on the basis of the primary disease. Common primary causes include congenital joint deformities, uneven joint surfaces, injuries, mechanical wear and tear, and metabolic diseases. Osteoarthritis often recurs especially when there is a change in the weather, exposure to cold, or exertion. Paying attention to keeping in shape, doing preparatory activities in advance when exercising, and preventing cold and keeping warm can reduce the probability of developing osteoarthritis to a certain extent.