Omeprazole and ranitidine can be taken together, but there is usually no need for both drugs to be taken at the same time. Omeprazole and ranitidine at the same time, usually does not cause drug interaction, but there is no need to take two drugs at the same time, these two drugs belong to the inhibition of gastric acid secretion of the drug, the role is the same, the two drugs to choose one of them can be. Omeprazole and ranitidine, can make the gastric acid secretion decrease, gastric enzyme activity decrease, in the clinic for the treatment of gastric ulcer, duodenal ulcer, chronic gastritis and so on. Taking omeprazole may cause nausea, vomiting, abdominal distension, constipation, diarrhea, dizziness, headache and other adverse reactions. It is contraindicated for those who are allergic to omeprazole, pregnant women, lactating women, and those with severe renal insufficiency. Taking Ranitidine may cause adverse reactions such as nausea, rash, fatigue, headache, dizziness. It is contraindicated in pregnant women, lactating women, and children under 8 years of age. It is recommended to apply the above two medicines under the guidance of a physician and not to take the medicine on your own.