The two sides of the corners of the mouth are white considering the following two possible conditions: first, seborrheic dermatitis, pale white in color, may have fine scales, mainly occurs in adolescent children, may be due to infection, or imbalanced diet, vitamin disorders or due to allergies and triggered. The second, consider vitiligo may be, mainly due to genetics, excessive ultraviolet radiation, trauma, neurological factors, immune disorders and other factors caused. In the treatment you can apply 0.03% tacrolimus ointment, or pimecrolimus ointment.