Pulmonary fibrosis generally refers to idiopathic pulmonary fibrosis, a chronic, progressive interstitial disease, the treatment is very limited and poor efficacy, there is no such thing as what to take to get better faster, the main role of current drug therapy is to slow down the progression of pulmonary fibrosis, to improve the quality of life and prolong survival. Currently, the main drugs used in the treatment of pulmonary fibrosis include pirfenidone and nidanib, which have anti-inflammatory, antifibrotic and antioxidant properties, and N-acetylcysteine, as an expectorant, which has an antioxidant and thus an antifibrotic effect at high doses (1800mg/d), which may be useful in some patients. Lung transplantation is currently the most effective treatment for pulmonary fibrosis. Lung transplant patients have greatly improved lung function after surgery, and their quality of life and survival duration have also been more significantly improved. Patients with pulmonary fibrosis should actively cooperate with the doctor’s treatment, and should not use medication on their own, blindly, in order to avoid delays or adverse reactions.