The cause of breast fibroma is not yet completely clear, and it has some relationship with endocrine disorders. Breast fibroma is mainly due to women’s ovarian function, estrogen level is too high, imbalance of regulation, and the patient’s response to estrogen is sensitive, under the long-term stimulation of estrogen, it can cause excessive proliferation of breast epithelial and fibrous tissues, structural disorders to form tumors. And endocrine imbalance can cause hormone imbalance, so breast fibroma has some relationship with endocrine imbalance. In addition, the formation of breast fibroma may be related to ionizing radiation, radiation, ultraviolet radiation and other factors; it may be related to bad dietary habits, eating spicy, greasy, stimulating food. Therefore, endocrine disorders should be consulted in time, and targeted treatment should be given by doctors to avoid serious impact on health.