Paroxysmal pain in the right breast and axilla of middle-aged women may be related to breast hyperplasia, ductal tumor of the breast, acute lymphatic inflammation and so on. 1. Breast hyperplasia: it is a relatively common disease, mainly related to endocrine changes, which can be manifested as breast pain, which can be radiated to axillary pain, and will change with menstrual cycle. 2. Ductal tumor of breast: ductal tumor of breast belongs to benign lesions, when ductal tumor of breast occurs in the right side, it will appear as pain in the right breast, and it can radiate to the axilla to produce pain symptoms. 3. Acute lymphadenitis: generally acute infection of axillary lymph nodes, which may cause redness and swelling of axilla, enlargement of lymph nodes, pain will be aggravated when pressing, and may also cause right chest pain. Middle-aged women with right chest and axillary pain also need to exclude trauma, heart disease, liver and gallbladder disease, etc. It is recommended to go to the hospital for a detailed examination to find out the cause of the problem and then treated under the guidance of the doctor.