Whiteheads on acne, which are white pus spots on acne, can be dealt with by treatments such as general treatment, topical medication and oral medication. 1. General treatment: Choose suitable cleansing products to remove excess oil on the skin surface. Avoid squeezing and scratching the lesions with hands. Appropriately limit the intake of high glycemic index foods and milk that may trigger or aggravate acne, keep bowel movement smooth, and avoid staying up all night. 2. Topical medication: topical benzoyl peroxide gel can kill Propionibacterium acnes, dissolve pimples and astringent effect, or topical fusidic acid can be used to fight infection. 3. Oral medication: Tetracycline antibiotics such as minocycline can be taken orally for anti-infection treatment. Acne is a kind of chronic inflammatory skin, it is recommended to consult a doctor in a timely manner, in the treatment must strictly comply with the doctor’s prescription medication, to reduce the emergence of adverse drug reactions.