Conservative treatments for gastrointestinal perforation include general treatment, drug treatment and so on. 1. General treatment: fasting, gastrointestinal decompression, parenteral nutritional support are recommended, and ice packs can be used to reduce temperature for patients with fever. 2. Drug therapy: patients with bacterial infection can use antibiotics such as penicillin, and can also use acid inhibitors such as omeprazole and lansoprazole to inhibit the secretion of gastric acid and reduce the gastric acid that enters into the abdominal cavity; those with severe abdominal pain can use scopolamine for pain relief. For serious conditions, non-surgical treatment is ineffective, suspected cancer and other cases need to consider surgical treatment. Patients diagnosed with gastrointestinal perforation should actively cooperate with the doctor and strictly follow the doctor’s instructions to avoid delaying the condition.