Vaginitis is the inflammation of the vagina. The vagina of normal healthy women has natural defenses against pathogenic invasion due to the characteristics of its anatomical organization. For example, the closure of the vaginal opening, the close proximity of the anterior and posterior vaginal walls, the proliferation of vaginal epithelial cells under the influence of estrogen and the keratinization of superficial cells, the balance of vaginal pH, which inhibits the reproduction of pathogens adapted to alkalinity, and the alkaline mucus of the cervical canal, make it easy for pathogens to invade and cause vaginal inflammation when the natural defenses of the vagina are disrupted. Normally there are aerobic and anaerobic bacteria that reside in the vagina and form a normal vaginal flora. If the ecological balance between the vagina and the flora is disrupted for any reason, conditionally pathogenic bacteria can also develop. Clinically, bacterial vaginosis, Candida vaginitis, Trichomonas vaginitis, senile vaginitis, and vaginitis in young women are common. Pregnant women are susceptible to Candida vaginitis because of the local vaginal environment and immune function. Vaginal suppositories are usually chosen for Candida vaginitis in pregnant women instead of using oral antifungals. The safer one to use during pregnancy is Kenitin. The main purpose of using antifungals during pregnancy is to control symptoms, and it is not necessary to have a definite fungal conversion if symptoms are not significant and medication is not effective. A proportion of virgins also get Candida vaginitis and the treatment regimen is similar to that of non-virgins. Medications can be used orally or as vaginal suppositories. Most hymens have a middle hole and most can fit more than one finger through, so most medications can be inserted. However, if a virgin needs a vaginal plug it is recommended that it be used under medical supervision. The use of oral medications is the same as for non-virgins. Most medications commonly used clinically for the treatment of Candida vaginitis have mild side effects. Oral medications are mainly associated with liver impairment and vaginal suppositories are mainly associated with local irritation. Any drug-related discomfort requires prompt consultation with a physician. In contrast, oral antifungal drugs, especially long-term use of oral antifungal drugs requires assessment of liver function.