Tumor recurrence and metastasis are the core problems of tumor treatment failure and affect survival. Among them, malignant ascites caused by tumor abdominal metastasis or peritoneal infiltration is a common clinical complication of malignant tumors, with a typical median survival of only a few weeks to a few months and a 1-year survival rate of <10%< span="">. Common tumors causing this condition include: stomach cancer, colorectal cancer, pancreatic cancer, liver cancer, ovarian cancer, uterine cancer, lymphoma, etc. For such cases, in addition to symptomatic treatment and passive ascites drainage, warm peritoneal perfusion chemotherapy has shown some clinical effectiveness. This method kills metastatic tumor cells through three ways: 1. Higher temperature (43~45℃) acting on human tumor cells can lead to their apoptosis or necrosis; 2. Higher local concentration of chemotherapeutic drugs in the peritoneal cavity can act directly on tumor cells; 3. High temperature has a sensitizing effect on chemotherapeutic drugs.