A middle-aged man snored like thunder for many years, and the examination found that it was caused by a huge tumor at the base of the skull. Today, otorhinolaryngology-head and neck surgeons of Hunan Provincial People’s Hospital resected this duck-pear-sized tumor endoscopically. According to literature statistics, this case is the first case of endoscopic resection of parapharyngeal space tumor at the base of the skull in Hunan Province. 47-year-old Tang Long (a pseudonym) lives in Shuangpai County, Yongzhou City, for more than a decade, he always snores when he sleeps, causing his family to complain, and in recent years, he feels as if something is stuck in his throat when he swallows. At first, Tang Long suspected that he had tonsillitis, medication, injections have not improved, and later suspected that the pharyngeal abscess, to the hospital for puncture, but also did not find the cause of the disease. Since this year, Tang Long pharyngeal discomfort and snoring phenomenon is becoming more and more serious, to the hospital to do an MRI only to find that the parapharyngeal space at the base of his skull grew a huge tumor, the tumor diameter of 4 × 7cm2, the size of a duck pear. Doctors told him that due to the large diameter of the tumor, the left side of the tonsil extrusion displacement, and block the airway, causing him to snore like thunder. This afternoon, the doctor in the endoscopic direct vision, the tumor peeled out, after pathological section examination, confirmed for nerve sheath meningioma. According to the chief surgeon, Professor Xiao Xuping, Director of Otorhinolaryngology-Head and Neck Surgery of Hunan Provincial People’s Hospital, compared with the traditional surgical method, removing the tumor of the base of the skull under the direct vision of endoscopy can clearly see the boundary of the tumor and the relationship between the tumor and the surrounding nerves and blood vessels, which facilitates the complete separation of the tumor and effectively avoids the damage to the nerves and blood vessels, leading to choking, hoarseness, pharyngeal fistulae, interspace Complications such as choking, hoarseness, pharyngeal fistula, and interstitial infection due to damage to nerves and blood vessels can be effectively avoided.