The feeling of worms wriggling in the anus may be caused by intestinal parasites, hemorrhoids, perianal eczema and other reasons. 1. Intestinal parasites: generally include roundworms, pinworms, hookworms and other parasites, such parasites will be active near the anus at night or lay eggs near the anus, which will cause perianal skin mucous membranes tingling as well as the feeling of worms wriggling. 2. Hemorrhoids: generally due to frequent consumption of spicy and irritating foods or sedentary standing and other reasons, there may be hemorrhoids prolapse, pain, blood in the stool and other symptoms, internal hemorrhoids prolapse will stimulate the anus, resulting in anal overflow from the anus, so it will be felt inside the anus worms worms wriggling. 3. Perianal eczema: generally due to bacterial infection, usually appear anal flushing, anal wetness and other phenomena, due to the skin around the anus is more moist, so it will feel the worm wriggling in the anus. Feeling worms wriggling in the anus may also be other reasons, it is recommended to go to the hospital in time to check the diagnosis, follow the doctor’s instructions to give treatment; daily life should pay attention to anal hygiene and cleanliness, at the same time pay attention to keep the local dry.