One ear pain may be caused by otitis externa, boils on the external auditory canal, middle ear inflammatory diseases, need to be treated for specific diseases, you can take oral antipyretic and analgesic drugs, non-steroidal anti-inflammatory drugs to relieve pain. 1. One side of the ear pain may be auricular local skin infection, auricular cartilage inflammation, if the symptoms are mild, you can apply anti-inflammatory ointment, if serious, you need anti-inflammatory drugs, such as levofloxacin ear drops to treat. 2. There may also be otitis externa, boils on the external auditory canal, which are caused by skin infections, due to the tight adhesion of the skin and cartilage of the external auditory canal, so the inflammation and swelling of the external auditory canal will have the symptom of earache, and can be orally relieved by analgesic medicines, such as acetaminophen, ibuprofen and so on. 3. Middle ear diseases such as herpetic tympanitis, acute suppurative otitis media, can also cause one side of the ear pain, mostly due to cold and flu, rhinitis, sinusitis, acute tonsillitis caused by the commonly used pain medication is a non-steroidal drug, such as diclofenac sodium extended-release tablets, ibuprofen extended-release capsules. The best way to stop pain is to clarify the cause of the disease, the cause of the treatment of disease, the above drugs need to be taken under the guidance of a doctor, to avoid the application of self-induced adverse consequences.