Amylase, including serum amylase and urinary amylase, are important in the diagnosis of acute pancreatitis. However, alcohol and some drugs such as asparaginase, aspirin, anticholinergic drugs, medullary collaterals diuretics, methyldopa, codeine or oral contraceptives and pentazocine can also increase the measured value of serum amylase, thus affecting the amylase test results: 1. Serum amylase: High serum amylase is mainly seen in acute pancreatitis, but also in pancreatic cancer, cholecystitis, cholangitis, pancreatic duct or bile duct obstruction The high serum amylase is mainly seen in acute pancreatitis, pancreatic cancer, cholecystitis, cholangitis, pancreatic duct or bile duct obstruction, mumps, peritonitis, acute appendicitis, renal failure or renal insufficiency, intestinal obstruction, ulcer perforation, ruptured tubal ectopic pregnancy, etc. However, the elevation of serum amylase is generally smaller in these diseases; 2. urinary amylase: high urinary amylase is later than serum amylase but lasts longer, and is also an important criterion for the diagnosis of acute pancreatitis. In addition, bile duct stones, biliary ascariasis, mumps, sepsis, hyperlipidemia, hypercalcemia, etc. can also cause elevated urinary amylase. The danger of high amylase can be understood as the clinical manifestations of acute pancreatitis, including severe abdominal pain with nausea, vomiting, mild fever, and even organ failure in the early stages. If the disease continues to progress, it can be complicated by complications such as pancreatic fistula, pancreatic abscess, and left-sided portal hypertension. If the pancreas and surrounding necrotic tissues become secondary to infection, there will be severe abdominal wall bulging, which may be accompanied by cardiac, pulmonary and renal insufficiency. Moreover, the prognosis of mild pancreatitis usually leaves no sequelae, while the mortality rate of severe cases is about 15%, and it is prone to complications such as pancreatic pseudocysts, abscesses and splenic vein embolism, leaving different degrees of pancreatic insufficiency.