Gastrointestinal bleeding mainly includes upper gastrointestinal bleeding, lower gastrointestinal bleeding and so on, according to the specific situation to choose the appropriate method of hemostasis, specifically including drug treatment, surgical treatment and so on. 1. Upper gastrointestinal bleeding: non-variceal rupture bleeding, you can choose to inhibit gastric acid medication, such as omeprazole, lansoprazole, etc.; unexplained non-variceal upper gastrointestinal bleeding can choose endoscopic treatment. Variceal rupture bleeding can be treated with drugs such as growth inhibitor, octreotide, terlipressin, etc. Serious cases need balloon compression and emergency surgery. 2. Lower gastrointestinal bleeding: (1) Hemorrhoidal bleeding can be treated with hemorrhoidal ointment or hemorrhoidal suppository, or with rectal suppository, ligation therapy. (2) Lower gastrointestinal bleeding caused by ulcerative colitis requires treatment of the primary disease and symptomatic management of the bleeding. (3) If it is a lesion of the blood vessels, endoscopic hemostasis is needed, followed by vascular intervention such as embolization. (4) If the lower gastrointestinal bleeding is caused by various tumors, the primary tumor needs to be removed by surgical methods. When gastrointestinal bleeding occurs, it is necessary to stop bleeding according to the specific situation, and it is recommended to follow the doctor’s instructions for proper treatment. All the above medications should be used under doctor’s guidance, avoid self-medication.