Adrenal tumors are mainly divided into adenomas with endocrine function and malignant tumors with infiltrative growth, and these diseases need to be differentiated. The diagnosis is as follows: First, and the most common adrenal occupying lesion is aldosterone tumor, the main symptom of which is the occurrence of hypertension and hypokalemia syndrome. Aldosterone tumors should be considered in patients with significant hypertension and adrenal masses. Secondly, adenomas with cortisol-producing function, such patients will have hypertension, weight gain, easily fallen, diabetes mellitus and centripetal obesity, and patients can undergo dexamethasone suppression test to determine whether they belong to this type of disease. Metastases from malignant tumors are the second most common cause of adrenal occupancy, and many malignancies will metastasize to the adrenal gland in the advanced stages of the disease. Malignant tumors such as breast cancer, lung cancer and renal cell carcinoma are more likely to metastasize to the adrenal gland. The most important way to determine whether an adrenal occupancy is a benign or malignant tumor is to perform MRI, PETE-CT and combine it with pathological examination for an accurate determination.