Multiple enlarged lymph nodes in the pelvis are generally considered to be caused by the reactive hyperplasia and enlargement of peripheral lymph nodes due to pelvic inflammation, or due to the metastasis of pelvic malignant tumors (e.g., ovarian, cervical, colorectal, prostate cancers, etc.) to the lymph nodes in the region, resulting in enlargement of lymph nodes caused by secondary lymph node malignant tumors. In order to clarify the exact cause of enlarged pelvic lymph nodes, one should consult the hospital in time to improve the laboratory and imaging tests, and if necessary, do a biopsy of the enlarged lymph nodes, and through the pathological examination of the biopsy tissue, the nature of the enlarged lymph nodes will be finally diagnosed. If the swelling is caused by inflammatory diseases, cephalosporin or quinolone broad-spectrum antibiotics (e.g., levofloxacin, moxifloxacin, etc.) can be given. If the pelvic lymph node enlargement is caused by malignant tumor, depending on the stage of the malignant tumor, surgery or radiotherapy (such as cisplatin, carboplatin, paclitaxel, etc.) and other treatment measures will be taken.