Patients with rectal cancer that has spread, i.e., distant metastases, have a survival time ranging from 1-3 years. Because of the distant metastasis of rectal cancer, targeted treatment options are also available. For primary tumors, palliative resection can be chosen because the tumor is prone to complicate intestinal obstruction in later stages. For metastatic lesions with liver metastases, systemic intravenous chemotherapy can be chosen to control the development of tumor, and radiofrequency ablation can also be chosen according to the location and characteristics of the lesion, and for liver metastases with obvious feeding vessels, hepatic artery cannulation and perfusion chemotherapy or hepatic artery embolization can be performed. Patients with pulmonary metastases can also choose radiofrequency ablation treatment, and concurrent pleural effusion can also be intermittently drained by thoracentesis under local anesthesia, which can reduce the patient’s symptoms and improve the quality of life in the late stage.