Painful urination requires a choice of anti-inflammatory medications after the cause of the problem has been identified, usually a urinary tract infection, kidney stones or traumatic irritation, respectively. The medications taken include antibiotics, non-steroidal anti-inflammatory drugs and so on. 1. Urinary tract infection: If there are symptoms such as painful urination and urgency, antibiotic drugs such as levofloxacin capsule or cefixime capsule can be taken orally after routine urinalysis to determine that there is a urinary tract infection. 2. Kidney stones: If you have kidney stones and urinary pain, you can first undergo extracorporeal shock wave lithotripsy, and then take non-steroidal anti-inflammatory drugs such as diclofenac sodium capsule orally after lithotripsy. 3. Traumatic stimulation: If urinary pain occurs after trauma, you can choose to take oral acetaminophen tablets and observe whether the pain improves. The above only lists some of the causes and the corresponding anti-inflammatory drugs, it is recommended that the patient should go to the urology department of the hospital as soon as possible for a comprehensive examination and to cooperate with the doctor’s diagnosis and treatment.