High-risk infants are newborns with high-risk factors during the fetal, delivery and neonatal periods. The consequences may be central coordination disorder, brain injury syndrome, cerebral palsy, mental retardation, behavioral abnormalities, speech impairment, hearing impairment, visual impairment, epilepsy, etc. Common high-risk factors are: prematurity, amniotic fluid contamination, premature rupture of amniotic fluid, umbilical cord encirclement, fetal malposition, very low birth weight babies, neonatal asphyxia, obstructed labor, occurring brain tissue hemorrhage, severe jaundice, neonatal ischemic-hypoxic encephalopathy, etc.