The persistent state of asthma is a very serious clinical state of asthma, which means that after conventional treatment is ineffective, the patient’s symptoms are very serious, and the asthma symptoms last for more than 12 hours. The clinical manifestations of patients with persistent asthma are mainly inability to lie down, agitation, non-stop wheezing, and at the same time there will be irritability, profuse sweating, incoherent speech, and a significant increase in the number of respirations, which can even be >30 breaths/minute. At the same time, the patient may experience assisted respiratory work, such as the triple-concave sign, and the patient’s heart rate will also increase, usually >120 beats per minute, and may even have a strange pulse. Rales can be heard in the full lungs of the patient, and in particularly severe patients, the rales appear to disappear, which is the silent lung. If you encounter this situation, it suggests that the patient’s asthma is very serious, must be timely treatment and rescue, the treatment mainly includes oxygen therapy, dilate the bronchial tubes, as well as the application of hormones and other forms of treatment.