The process of checking pregnancy is as follows: i. Determination of intrauterine pregnancy. It can be determined by the following methods: early pregnancy test paper measurement, urine pregnancy test, serum HCG and progesterone measurement, B-mode ultrasonography (gestational sac visible at 4 weeks of pregnancy; yolk sac visible at 5-6 weeks of pregnancy; embryonic bud and fetal heartbeat visible at 6-7 weeks of pregnancy). Establish maternal health handbook, project the expected date of delivery, and assess the high-risk factors during pregnancy. Routine blood, urine, blood group, liver function, kidney function, fasting blood sugar, hepatitis B, syphilis, HIV antibody, etc. IV. Health education, nutrition and lifestyle guidance, supplementation of folic acid 0.4mg/d, cautious use of drugs and vaccines, and change of poor lifestyle habits.