Once a skull defect is made, a skull repair is required. Patients will be in constant danger if the skull defect is not repaired in time. It is easy to be injured by external invasion, which is very dangerous and sometimes may even be fatal. Cranial defect may also cause unstable intracranial pressure, the cerebrospinal fluid circulation and blood circulation in the skull are affected, the neurological functions and life activities cannot function normally, and it may also cause cranial defect syndrome. Most patients also suffer from long-term depression due to the unattractive appearance of the skull. Patients who have undergone cranioplasty have a new cranial bone, which restores the original appearance of the skull and improves the appearance of the skull. In addition, a complete cranial bone can play a strong role in protecting the brain and soft tissues inside the skull by rebuilding a closed and stable cranial cavity environment and ensuring the good operation of intracranial blood circulation, cerebrospinal fluid circulation and various neurological functions. As a major factor affecting the postoperative effect of cranial repair, it is very important to choose the right material. In hot and cold environments, headaches and dizziness may occur; in titanium mesh overlay repair, the edges of the material may cause cutting injuries to the scalp; and the histocompatibility of the titanium mesh is not very good, which may lead to rejection or postoperative infection, or even destruction of the scalp tissue, resulting in the exposure of the titanium mesh. If a patient has an exposed titanium mesh, it is recommended to go to the hospital for detailed examination and treatment as soon as possible. If necessary, the titanium mesh can be surgically removed and the peek material can be repaired after the scalp has recovered and healed. Our peek cranioplasty has greatly improved the overall aesthetics. It has been recognized and praised by patients.