Primary thrombocythemia is usually difficult to cure and cannot be completely eradicated, but the progression of the disease can be controlled by medication. 1. Primary thrombocythemia is a chronic myeloproliferative disorder characterized by a persistent increase in bone marrow megakaryocytes and thrombocytosis, which usually leads to bleeding and enlargement of the spleen, and there is no specific way to cure the disease. 2. Patients with primary thrombocythemia can be treated with aspirin, hydroxyurea, and interferon as prescribed by the doctor, which can prevent bleeding and thrombosis, and also inhibit platelet production, which can achieve a good control effect. The use of drugs during treatment should follow the guidance of professional physicians.