There are many reasons for generalized bone pain, the more common ones are kidney disease and tumor disease. 1. Kidney disease: for example, renal insufficiency, chronic renal failure, etc. When kidney function is damaged, resulting in calcium and phosphorus metabolism disorders, which will affect bone metabolism, bone decalcification, poor calcification, will cause generalized bone pain. The condition can be treated with oral lanthanum carbonate and sevelamer carbonate as prescribed by doctor. 2. Tumor disease: it is mostly primary tumor of bone, but it may also be caused by other tumors that metastasize to bone, such as lung cancer, liver cancer with bone metastasis, etc. The pain caused by this factor can be treated by doctor’s prescription. Pain caused by this factor can be treated with oral aspirin for pain relief and local radiotherapy. It should be noted that all the above treatments should be carried out under the guidance of doctor. Generalized bone pain may also be caused by colds, rheumatism, osteoporosis and other factors, and it is recommended to consult a doctor in time to clarify the cause and then carry out targeted treatment.