Infertility is defined as a diagnosis of infertility when a couple has had normal sexual intercourse for more than 1 year after cohabitation and has not conceived without contraception. There are many causes of infertility. When there is a history of infertility for more than one year, both partners should go to the male and female departments of the reproductive center for separate examinations. The male partner will go to the male fertility center to check the semen routine, physical examination, sexual function test, sperm DNA fragmentation, and the presence of combined hepatitis B, syphilis, and AIDS diseases. For the female partner, in addition to the normal physical examination and routine blood biochemical examination mentioned above, some special tests are needed, such as tubal imaging to check whether the fallopian tubes are open, whether there is any obstruction to ovulation, and whether the uterine cavity is combined with organic lesions, such as endometrial polyps and fibroids, which can affect embryo fertilization. Once the cause is identified, the couple can then address the cause and carry out targeted treatment to help the couple conceive again after the cause of infertility is cured, or through assisted reproduction techniques such as artificial insemination or IVF if natural conception is still not possible.