The main ingredient of Betalock is metoprolol tartrate. Bisoprolol and metoprolol tartrate can usually be replaced as prescribed by the doctor. 1. Bisoprolol is a highly selective β1-adrenergic receptor blocker, which is mainly applied to hypertension, coronary heart disease, chronic stable heart failure with ventricular hypocontractility. 2. Metoprolol tartrate is also a β1-adrenergic receptor blocker, mainly used for hypertension, angina pectoris and other diseases. 3. The two belong to the same type of drug can be replaced under the guidance of the doctor, without the need for transition. It should be noted that the plasma half-life of bisoprolol after administration is 10~12 hours, and its drug effect can be maintained in the plasma for 24 hours. Metoprolol tartrate reaches effective concentration 1~2 hours after administration and can be maintained for 3~4 days, the specific dosage is recommended to be used according to the doctor’s instruction. It is recommended to standardize the treatment under the guidance of a doctor, and not to use the drug blindly by oneself.