There is no “best” treatment for keloid scars, but there are options such as glucocorticoids, 5-fluorouracil and other medications, surgery, etc. Keloid scars are benign skin growths caused by overgrowth of connective tissue in the skin, often secondary to skin injury. Keloids are benign skin growths caused by overgrowth of connective tissue in the skin, often secondary to skin injury. It is recommended to consult a dermatologist or plastic surgeon to choose the appropriate treatment according to the size and location of the skin lesion, but it is easy to recur after treatment. Small keloids, except for those in the ear and those containing foci of infection, are usually treated with drug injections, commonly used glucocorticosteroids such as trimethoprim combined with 5-fluorouracil intradermal injections, and can also be supplemented with laser treatments and other treatments. Small keloids in the ear and with infected foci, as well as medium to large keloids, require surgical treatment to completely remove the keloid, and at the same time, radiation therapy, 5-fluorouracil injections, etc. to prevent recurrence. All of the above treatments need to go to a regular medical institution and follow the doctor’s instructions to choose the appropriate treatment plan to avoid adverse consequences.