Primary urethra is relatively rare in clinical practice. Malignant tumors include cancer, sarcoma, melanoma, etc. In the early stage, there can be symptoms such as bleeding from the urethra, frequent urination, urgent urination and painful urination. The tumor increases in size and also causes difficulty in urination. The treatment is difficult and the prognosis is poor. What diseases are male urethral cancer easily confused with? Male urethral cancer is a kind of malignant tumor disease of the urinary system. Many people are concerned about urethral cancer and worry about the serious consequences of having urethral cancer, and want to know what diseases male urethral cancer can be easily confused with. Urethral cancer should be distinguished from acromegaly, urethral stricture, periurethral abscess, tuberculosis and penile cavernous sclerosis. Biopsy should be performed if necessary. 1.Prostate hyperplasia Most commonly seen in elderly men, with progressive urinary difficulty as the main manifestation, and acute urinary retention may occur. The enlarged prostate can be palpated by rectal palpation and the middle groove disappears. A urethral mass cannot be palpated. Cystourethrography shows a negative image of the enlarged prostate above the pubic bone with no filling defect in the urethra. Urethral cystoscopy can be seen as a deformation of the bladder neck opening, the middle lobe or both lobes of the prostate enlarging protruding towards and squeezing the urethra. 2, urethral condyloma is a viral disease transmitted by sexual contact, mostly with other sexually transmitted diseases occurring at the same time. The most important thing is that it occurs in the mucosa of the navicular fossa or other parts of the urethra. There is burning pain when urinating and urethral discharge. There may also be penile warts, penile head and foreskin warts, scrotal warts, anal warts and other lesions. Urethroscopic observation is papillary, pointed needle-shaped, light red, soft new organisms. 3, urethral papilloma A benign tumor of the urethra, mostly located in the prostate urethra, often occurring at the same time as the bladder papilloma. There are symptoms such as frequent urination, painful urination, initial or final hematuria. During cystourethroscopy, it can be seen that there are papillary tumors with tips near the urethral inlet and seminal frenulum, and the terminal branches are in the shape of villi, which can drift with the perfusion fluid without ulceration on the surface. How to treat male urethral cancer? 1.Stage B and C tumors are suitable for partial penile excision at a distance of 1~2cm from the tumor. If a satisfactory tumor-free margin cannot be obtained, penile resection and perineal urethrostomy should be performed. After removal of the primary tumor, if the enlarged inguinal lymph nodes do not shrink and biopsy confirms cancer metastasis, deep inguinal, superficial lymph nodes and pelvic lymph node dissection should be performed. 2.Stage O and A tumors in the urethra of the penis are advocated to perform transurethral tumor electrosurgery. Since clinical staging is often not accurate enough, it is more reasonable to perform urethrotomy, penile or perineal urethrostomy at 1~2cm proximal to the tumor. 3. Stage O and A tumors in the urethral membrane or prostate can be electrically resected via urethra. As the electrodes are often incomplete, and the tumor near the sphincter is prone to urinary incontinence, it is more reasonable to perform cystoprostate and total urethrectomy. The pelvic lymph node dissection should be performed at the same time. If biopsy confirms inguinal lymph node metastasis, it should also be removed. Radiation therapy for male urethral cancer includes external irradiation and intra-tissue irradiation for small low-stage tumors, and radiation therapy for large high-stage posterior urethral cancer is satisfactory. The high concentration of urine will produce some stimulation to the prostate gland, and long-term bad stimulation is harmful to the prostate gland. Drinking more water can not only dilute the blood, but also effectively dilute the concentration of urine. 2, do not hold urine: bladder full with the intention to urinate should urinate, hold urine is not good for the bladder and prostate. The first thing you should do before taking a long bus is to empty your urine, and if you are in a hurry to urinate during the bus ride, you should greet the driver and get off the bus to urinate, don’t hold it in. The actual fact is that you can find a lot of people who are not able to get a good deal on this. 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In addition, it is necessary to insist on flushing the external genitalia every time you have intercourse. 7, to prevent cold: do not sit on the cool stone for a long time, because the cold can make sympathetic excitement, enhance lead to increased pressure in the urethra and cause reflux. 8, avoid rubbing the perineum: rubbing will aggravate the prostate symptoms and make the patient significantly uncomfortable. In order to prevent local harmful abrasion, one should ride a bicycle less often, let alone for a long time or a long distance on a bicycle or motorcycle. 9, regulate life: should try not to drink alcohol, eat less chili and ginger and other spicy stimulating food, in order to avoid making the prostate and bladder neck repeatedly congested, aggravating the feeling of local distension and pain. 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