Side effects of chemotherapy include near-term adverse reactions such as myelosuppression, alopecia, gastrointestinal reactions and long-term adverse reactions such as reproductive toxicity and second tumors. 1. The most common near-term adverse reactions are gastrointestinal reactions, such as nausea, vomiting, mucositis, etc. Myelosuppression is a common adverse reaction of cytotoxic antitumor drugs, which is mainly manifested by the reduction of white blood cells, red blood cells and platelets. Other common adverse reactions include alopecia, cardiotoxicity, hepatotoxicity, neurotoxicity, pulmonary toxicity, urinary toxicity and so on. 2. Long-term adverse reactions, mainly reproductive toxicity, manifested as the occurrence of teratogenicity and infertility; and the occurrence of second tumors, such as lymphoma, leukemia and bladder cancer.