Timely treatment of mild forms of plague may not affect survival, but if the disease is severe, it can be fatal within a week, depending on the type and treatment. Plague is a virulent infectious disease, currently in the clinical classification of light, pulmonary, glandular and septicemia type four. In general, patients with mild plague can be treated with relevant medications and are generally safe. Patients with pneumonic plague may die within one or two days due to heart failure, shock and other factors if they are not treated promptly. Patients with glandular plague usually develop very quickly, reaching peak status in two to four days, with enlarged lymph nodes all over the body. If no timely treatment is given, the enlarged lymph nodes will rapidly turn into pus and break down, and death can be caused by severe toxemia, septicemia, and secondary pneumonia within a week’s time. Patients with septicemic plague usually quickly develop systemic toxemia symptoms, central nervous system symptoms and severe bleeding phenomenon, which will lead to the patient quickly into a coma, and often die within three days if not rescued.